The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2002

Filed:

Feb. 24, 1999
Applicant:
Inventors:

Floyd E. Taub, Silver Spring, MD (US);

Carol H. Pontzer, Silver Spring, MD (US);

Assignee:

Dovetail Technologies, Inc, College Park, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1275 ; A61K 3/1215 ;
U.S. Cl.
CPC ...
A61K 3/1275 ; A61K 3/1215 ;
Abstract

The present invention relates to methods of using peptide-like compounds, e.g., aminocarboxylic acid amide derivatives, to bias the immune system toward producing, enhancing, or maintaining a polarized Th1 response, and to methods for treating diseases that improve by creating a Th1 response. The invention also relates to a method of treating diseases associated with elevated soluble TNF alpha levels by administering beta-alethine together with NAC to reduce soluble TNF alpha, and to a pharmaceutical composition comprising same. The present compounds can be used to modulate cytokines including IFN-gamma and IL-10.


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