The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2002
Filed:
Jan. 24, 2000
Yuji Kikuchi, Ryugasaki, JP;
Abstract
A method for measuring luminol enhancing light emission without separating leukocytes and erythrocytes, that is, using whole blood and a method for measuring the number of leukocytes trapped by the capillary bed or the time required for leukocytes to pass through the capillary bed to thereby provide an effective index for ability of leukocytes to protect infection and for oxidative stress caused by leukocytes are provided. Specifically, a method is provided for measuring an amount of active oxygen produced by leukocytes and oxidative stress, where the method includes allowing an anticoagulated whole blood sample collected from a human or an animal to pass through a microchannel array including a substrate with a fine channel array arranged on its surface and a transparent substrate which is adhered onto the substrate by contact bonding, and measuring a light emission level from whole leukocytes passing through the microchannel array through the transparent substrate to use the measured light emission level as an index of an amount of active oxygen produced by leukocytes and oxidative stress.