The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2002

Filed:

Jan. 11, 1994
Applicant:
Inventors:

Phillip D. Cook, Carlsbad, CA (US);

Oscar L. Acevedo, San Diego, CA (US);

Peter W. Davis, Carlsbad, CA (US);

David J. Ecker, Leucadia, CA (US);

Normand Herbert, San Marcos, CA (US);

Assignee:

ISIS Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/800 ; C07K 1/700 ; C12Q 1/68 ;
U.S. Cl.
CPC ...
A61K 3/800 ; C07K 1/700 ; C12Q 1/68 ;
Abstract

Novel ethylene glycol compounds bearing various functional groups are used to prepare oligomeric structures. The ethylene glycol monomers can be joined via standard phosphate linkages including phosphodiester and phosphorothioate linkages. Useful functional groups include nucleobases as well as polar groups, hydrophobic groups, ionic groups, aromatic groups and/or groups that participate in hydrogen-bonding.


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