The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2002

Filed:

Nov. 30, 1999
Applicant:
Inventors:

Makoto Takemura, Tokyo, JP;

Hisashi Takahashi, Tokyo, JP;

Kazuyuki Sugita, Tokyo, JP;

Rie Miyauchi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/147 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/147 ; C07D / ;
Abstract

Substituted cyclobutylamine derivativesb with a novel structure represented by the following formula (I), wherein R to R and Q each represents a specific substituent and, in particular, Q represents a quinolone derivative having a specific structure. These derivatives are useful as antibacterial compounds which have excellent antibacterial activity against a wide scope of bacteria including Gram-negative and Gram-positive bacteria, exert potent antibacterial activity particularly against methicillin-resistant Staphylococcus aureus (MRSA) strains, penicillin-resistant pneumococcus strains and quinolone-resistant bacteria, and are also possessed of both excellent pharmacokinetics and high safety.


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