The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2002
Filed:
Feb. 18, 2000
Applicant:
Inventor:
Ya-Ming Hou, Philadelphia, PA (US);
Assignee:
Thomas Jefferson University, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/00 ; C12N 1/20 ; C12Q 1/68 ; C12P 1/934 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 1/00 ; C12N 1/20 ; C12Q 1/68 ; C12P 1/934 ; C07H 2/104 ;
Abstract
A method of inhibiting activities of a tRNA of a selected pathogen is provided wherein a cell infected with a selected pathogen is contacted with an effective amount of an oligonucleotide targeted to a region of the cloverleaf structure of a tRNA of the selected pathogen. Compositions for inhibiting activities of a tRNA of a selected pathogen which contain an oligonucleotide targeted to a region of cloverleaf structure of a tRNA of the selected pathogen are also provided. In addition, methods of killing the pathogen with these compositions are provided.