The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2002
Filed:
Mar. 15, 2000
Applicant:
Inventors:
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/500 ; C12N 1/563 ; C12N 1/585 ; C12Q 1/68 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 1/500 ; C12N 1/563 ; C12N 1/585 ; C12Q 1/68 ; C07H 2/104 ;
Abstract
The present invention relates to nucleic acid molecules encoding hypusines mutants having the biological activity of an inhibitor of cellular proliferation. The present invention further relates to vectors comprising said nucleic acid molecules, to hosts transformed with said vectors, to methods of producing the polypeptide encoded by the nucleic acid molecule of the invention as well as to the polypeptide itself. In addition, the present invention relates to pharmaceutical and diagnostic compositions comprising one or more of the aforementioned compounds, the methods for synchronizing cell growth and to the use of the vector of the invention in gene therapy.