The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2002
Filed:
Dec. 08, 1999
Yasuo Nagasawa, Tokyo, JP;
Hideaki Yoshida, Tokyo, JP;
Institute of Cytosignal Research Inc., Tokyo, JP;
Abstract
A protein having transcription inhibitory activity and lacking at least a part of regions other than a region having DNA binding activity in a transcriptional regulatory factor is provided. This protein can be obtained by isolating cDNA encoding a protein capable of binding to the transcriptional regulatory region of the gene transcription of which is to be inhibited, deleting from the cDNA at least a part of the regions other than the region having DNA-binding activity, inserting the resulting DNA into an appropriate vector, introducing said vector into cells to allow them to express the deleted gene, and isolating and purifying a protein showing the transcription inhibitory activity. For example, the protein can be used in the field of pharmaceuticals as a therapeutic agent. Its use in the field of gene therapy is also expected.