The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2002
Filed:
Dec. 14, 1999
Elsie C. Jimenez, Quezon City, PH;
Baldomero M. Olivera, Salt Lake City, UT (US);
William R. Gray, Salt Lake City, UT (US);
Lourdes Cruz, Salt Lake City, UT (US);
University of Utah Research Foundation, Salt Lake City, UT (US);
Abstract
The present invention is directed to contryphan peptides having 6-12 amino acids, preferably including one or more D-tryptophan residues. More specifically, the present invention is directed to contryphan peptides having the general formula Xaa -Cys-Xaa -Xaa -Glu-Pro-Trp-Cys (SEQ ID NO:1), wherein Xaa is Gly or des-Xaa , Xaa is Pro or 4-trans-hydroxyproline and Xaa is D-Trp or L-Trp, preferably D-Trp. The present invention is further directed to the peptides contryphan R and des-Gly contryphan R. In contryphan R, Xaa is Gly and Xaa is D-Trp. These contryphans are useful as anticonvulsant or neuroprotective agents.