The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2002

Filed:

May. 25, 2000
Applicant:
Inventors:

Thomas Jeffrey Clark, High Point, NC (US);

Gary Maurice Dull, Lewisville, NC (US);

Dwo Lynm, Winston-Salem, NC (US);

Lan Miao, Winston-Salem, NC (US);

Craig Harrison Miller, Winston-Salem, NC (US);

Jeffrey Daniel Schmitt, Winston-Salem, NC (US);

Assignee:

Targacept, Inc., Winston-Salem, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K 3/1395 ; A61P 2/500 ;
U.S. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K 3/1395 ; A61P 2/500 ;
Abstract

The present invention relates to diazabicyclic compounds, and preferably N-aryl diazabicyclic compounds. Of particular interest are 2-pyridyl diazabicyclic compounds, such as (1S,4S)-2-(3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane. Other exemplary compounds of the present invention include: (1S,4S)-2-(5-(4-methoxyphenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane, (1S,4S)-2-(5-pyrimidinyl)-2,5-diazabicyclo[2.2.1]heptane and (1S,4S)-2-(6-chloro-3-pyridazinyl)-2,5-diazabicyclo[2.2.1]heptane. The present invention also relates to prodrug derivatives of the compounds of the present invention.


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