The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2002
Filed:
May. 17, 2001
Applicant:
Inventors:
Walter A. Szarek, Kingston, CA;
Xianqi Kong, Dollard-des-Ormeaux, CA;
Gregory R. J. Thatcher, Kingston, CA;
Boris Gorine, Edmonton, CA;
Assignee:
Queen's University at Kingston, Kingston, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/166 ;
U.S. Cl.
CPC ...
A61K 3/166 ;
Abstract
Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.