The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2002

Filed:

Jul. 28, 1999
Applicant:
Inventors:

Vimla Band, Waban, MA (US);

Qingshen Gao, Winchester, MA (US);

Assignee:

New England Medical Center, Boston, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/500 ; C12N 1/563 ; C12N 5/00 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 1/500 ; C12N 1/563 ; C12N 5/00 ; C07H 2/104 ;
Abstract

The invention relates to a putative human tumor suppressor protein identified as a novel GAP protein, designated “E6TP1” (for E6-targeted protein), its nucleic acid and amino acid sequences, and methods of use thereof in the regulation of small G protein signaling pathways. In addition, methods of use of E6TP1 as a Therapeutic for treatment or prevention of carcinomas, especially HPV-associated carcinomas of anogenital origin, and other diseases is encompassed in the invention.


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