The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2002
Filed:
Jun. 07, 1995
Kathryn J. Elliott, San Diego, CA (US);
Steven B. Ellis, San Diego, CA (US);
Michael M. Harpold, El Cajon, CA (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
Methods for identifying compounds which modulate the activity of human neuronal nicotinic acetylcholine receptors are provided. Invention methods employ DNAs encoding alpha and beta subunits of human neuronal nicotinic acetylcholine receptors, and the polypeptides encoded thereby. Test cells useful for conducting invention assays include mammalian and amphibian cells containing said DNA. Various combinations of subunits (i.e., one or more &agr; , &agr; , &agr; , &agr; , &agr; and &agr; subunits in combination with &bgr; , &bgr; and/or &bgr; subunits) can be employed for the invention assays.