The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2002
Filed:
Mar. 25, 1999
Applicant:
Inventors:
Kazuhiro Inoue, Tokyo, JP;
Hiroshi Susaki, Tokyo, JP;
Masahiro Ikeda, Tokyo, JP;
Hiroshi Kuga, Tokyo, JP;
Eiji Kumazawa, Tokyo, JP;
Akiko Togo, Tokyo, JP;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/1715 ; A61K 3/800 ; A01N 4/304 ; C07H 1/502 ; C08B 3/702 ;
U.S. Cl.
CPC ...
A61K 3/1715 ; A61K 3/800 ; A01N 4/304 ; C07H 1/502 ; C08B 3/702 ;
Abstract
A drug complex characterized in that a residue of a drug compound such as antineoplastic agents and a carboxy(C )alkyldextran polyalcohol obtained by treating a dextran under conditions that enable substantially complete polyalcoholization are bound to each other by means of a spacer comprising an amino acid or a spacer comprising peptide-bonded 2 to 8 amino acids. Said complex is characterized-in that it has excellent selectivity to tumorous sites so as to exhibit high antineoplastic activity and also achieves reduced appearance of toxicity.