The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2002

Filed:

Jan. 26, 2000
Applicant:
Inventors:

Sithamalli V. Chandramouli, Limerick, PA (US);

Michael K. O'Brien, Berwyn, PA (US);

Tory H. Powner, Chester, VA (US);

Assignee:

Aventis Pharmaceuticals Inc., Bridgewater, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07U / ;
U.S. Cl.
CPC ...
C07U / ;
Abstract

Methods for stereoselective substitution in which a (mono or un)-&agr;-substituted unprotected &bgr;-amino ester compound or salt thereof is reacted with an aliphatic electrophile in the presence of a base selected from alkyl lithium compounds, lithium hydride, lithium amide, lithium dialkyl amides and alkali hexamethyldisilylamines.


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