The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2002
Filed:
Sep. 13, 2000
Applicant:
Inventors:
Hugh W. Hoogendoorn, Ancaster, CA;
Alexander Duncan, Decatur, GA (US);
Michael J. Morris, South Bend, IN (US);
Assignee:
Other;
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/56 ; C12Q 1/00 ; C12Q 1/37 ;
U.S. Cl.
CPC ...
C12Q 1/56 ; C12Q 1/00 ; C12Q 1/37 ;
Abstract
The invention provides a one-stage method of measuring antithrombin (AT) activity in a sample. In the method, a diluted sample is mixed with AT-deficient plasma containing intrinsic coagulation enzymes, an AT augmenting compound such as heparin, a phospholipid and an activator of the contact phase of the intrinsic coagulation pathway. Following addition of calcium ions, coagulation time is measured and compared to a reference standard to determine the level of AT activity in the sample.