The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2002

Filed:

Apr. 03, 2000
Applicant:
Inventors:

Hidekazu Suzuki, Chuo-Ku, JP;

Satoshi Yamazaki, Chuo-Ku, JP;

Yoshikazu Naito, Chuo-Ku, JP;

Masanobu Takeuchi, Chuo-Ku, JP;

Yoshiaki Saito, Chuo-Ku, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/156 ; A61K 3/157 ; A61K 9/107 ; A61F 2/00 ; A61F 1/300 ;
U.S. Cl.
CPC ...
A61K 3/156 ; A61K 3/157 ; A61K 9/107 ; A61F 2/00 ; A61F 1/300 ;
Abstract

An O/W emulsion composition comprising fluorometholone or clobetasone butyrate, a phospholipid, an oil, a nonionic water-soluble cellulose derivative, and water. The O/W composition has advantages that fluorometholone or clobetasone butyrate contained therein is highly bioavailable and that the solubility of fluorometholone or clobetasone butyrate and the concentration thereof present in the composition can be kept stable. Thus, this composition is usable for the treatment of various inflammatory diseases by the generalized or local administration thereof. It provides a drug which shows an anti-inflammatory activity equal or higher than that of commercially available eye drops comprising a suspension of such an active ingredient even when it is applied in a smaller dose than that of commercially available one and further provides a drug having excellent storability, which reduces apprehension of systemic side effects of fluorometholone or clobetasone butyrate when it is applied to the eyes.


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