The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2002

Filed:

Aug. 02, 2001
Applicant:
Inventors:

Marek Kwiatkowski, Uppsala, SE;

Mats Nilsson, Stockholm, SE;

Ulf Landegren, Uppsala, SE;

Assignee:

Quiatech AB, Stockholm, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/100 ; C07F 9/02 ; C07F 7/02 ;
U.S. Cl.
CPC ...
C07H 2/100 ; C07F 9/02 ; C07F 7/02 ;
Abstract

The present invention relates to a support system for the solid phase synthesis of oligomers, such as oligonucleotide, wherein the starting compound is bound to the support via a disiloxyl linkage. Furthermore, the invention relates to a method for synthesis of oligonucleotides on a solid support. The support system comprises a stable disiloxyl linkage providing high nucleoside loadings to the support and the method allows convenient non-laborious oligomer synthesis.


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