The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2002
Filed:
Apr. 30, 1999
Applicant:
Inventors:
Stephen D. Mikolajczyk, San Diego, CA (US);
Tang Jang Wang, Poway, CA (US);
Harry G. Rittenhouse, Del Mar, CA (US);
Robert L. Wolfert, San Diego, CA (US);
Kevin Slawin, Houston, TX (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/3574 ; G01N 3/353 ; G01N 3/348 ; A61K 4/900 ; C12Q 1/00 ;
U.S. Cl.
CPC ...
G01N 3/3574 ; G01N 3/353 ; G01N 3/348 ; A61K 4/900 ; C12Q 1/00 ;
Abstract
A method of distinguishing prostate cancer from benign prostatic hyperplasia (BPH) is provided. The mathematical combination or ratio of proPSA and BPSA serum or tissue markers may be used for distinguishing benign prostatic hyperplasia (BPH) from prostate cancer. It is the discovery of the present invention that BPSA is preferentially elevated in transition zone prostate tissue whereas pPSA is elevated in the peripheral zone of prostate tissue. A kit for aiding in distinguishing BPH from prostate cancer is also provided.