The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2002
Filed:
Dec. 22, 1999
Applicant:
Inventors:
Shengfang Jin, West Roxbury, MA (US);
Andrew W. Shyjan, Nahant, MA (US);
Christophe Van Huffel, Cambridge, MA (US);
Assignee:
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/00 ; C12Q 1/02 ; G01N 3/353 ; G01N 3/3574 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/00 ; C12Q 1/02 ; G01N 3/353 ; G01N 3/3574 ;
Abstract
Increased expression of DR6 is associated with drug resistance of certain cells (e.g., cancer cells). The invention provides methods for identifying drug resistant cells by measuring the expression or activity of DR6, methods for identifying modulators of drug resistance, and methods for modulating drug resistance by modulating the expression or activity of DR6.