The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 16, 2002

Filed:

Apr. 14, 1998
Applicant:
Inventors:

Heinz Hartmut Seliger, Elchingen, DE;

Flavio Ramalho Ortigao, Ulm, DE;

Hannelore Rösch, Erbach, DE;

Rudi Rösch, Erbach, DE;

Bernd Krist, Ulm, DE;

Assignee:

Aventis Pharma Deutschland GmbH, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/102 ; C07H 2/104 ; C12Q 1/68 ; A01N 4/304 ;
U.S. Cl.
CPC ...
C07H 2/102 ; C07H 2/104 ; C12Q 1/68 ; A01N 4/304 ;
Abstract

The invention relates to oligoribonucleotide analogs with terminal 3′—3′ and/or 5′—5′ internucleotide linkages. This modification stabilizes the molecules altered in this way, including ribozymes, without adversely altering their properties, including, where appropriate, catalytic activities.


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