The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2002
Filed:
Nov. 30, 1994
Applicant:
Inventors:
J. Leighton Read, Palo Alto, CA (US);
Stephen P.A. Fodor, Palo Alto, CA (US);
Lubert Stryer, Stanford, CA (US);
Michael C. Pirrung, Mesquite, TX (US);
Paul D. Hoeprich, Jr., Danville, CA (US);
Assignee:
Affymetrix, Inc., Santa Clara, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/36 ; G01N 3/3543 ; A61K 3/800 ;
U.S. Cl.
CPC ...
C12M 1/36 ; G01N 3/3543 ; A61K 3/800 ;
Abstract
A method for synthesizing oligonucleotides on a solid substrate. The method provides for the irradiation of a first predefined region of the substrate without irradiation of a second predefined region of the substrate. The irradiation step removes a protecting group therefrom. The substrate is contacted with a first nucleotide to couple the nucleotide to the substrate in the first predefined region. By repeating these steps, an array of diverse oligonucleotides is formed on the substrate.