The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2002
Filed:
Feb. 24, 1995
Craig W Adams, Corona, CA (US);
Patty P. Y. Pang, Rancho Cucamonga, CA (US);
C. Marina Belei, Anaheim, CA (US);
Beckman Instruments, Inc., Fullerton, CA (US);
Abstract
The gene for DNase B has been cloned and vectors incorporating the cloned DNA have been used to transform , allowing efficient and rapid production of the DNase in without the necessity of growing large quantities of . The enzyme can be produced with a leader peptide at its amino terminus. An improved method for the purification of naturally occurring DNase B enzyme is also provided. The DNase B enzyme produced, either by purification of naturally occurring enzyme or by recombinant DNA techniques, can be used to generate antibodies and can also be used in immunochemical assays to detect the presence of anti-DNase B antibodies in serum as a marker of infection by