The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2002
Filed:
May. 26, 1999
Mitsunobu Yoshii, Tokyo, JP;
Shigeo Watabe, Tokyo, JP;
Daiichi Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
A prophylactic and/or therapeutic method for treating a disease caused by mitochondrial functional abnormality, or a disease with mitochondrial functional abnormality, including: administering a prophylactically and/or therapeutically effective amount to a patient in need of such treatment of a medicament including as an active ingredient a substance having a stabilizing effect on mitochondrial membrane by suppressing or eliminating depolarization of mitochondrial membranes which is caused by elevation of intracellular calcium ion concentration, wherein the stabilizing effect on mitochondrial membrane is an action of suppressing or eliminating depolarization of mitochondrial membranes, wherein the depolarization of mitochondrial membranes is caused by elevation of intracellular calcium ion concentration. The disease may be ischemic diseases, toxic diseases, or degenerative diseases. The medicament may be 2-oxo-1-pyrrolidinylacetic acid 2,6-dimethylanilide which acts as a benzodiazepine receptor antagonist.