The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2002
Filed:
Aug. 12, 1999
Gerd Grieninger, York, NY (US);
Dianne Applegate, York, NY (US);
Lara Stoike-Steben, Ann Arbor, MI (US);
New York Blood Center, New York, NY (US);
Abstract
The invention provides novel &agr; CX cleavage fragments of fibrinogen and methods for detecting and purifying these fragments. The method of the invention also includes a diagnostic method for determining fibrinolytic states or atherogenesis in a mammal. Methods of treating disease characterized by fibrinogen metabolism are also disclosed. In addition, the invention also provides monospecific antibodies which are specifically reactive with &agr; C domain of fibrinogen. Also provided, are DNA and RNA molecules that encode &agr; C cleavage fragments of fibrinogen. In addition, the present invention includes a vector and a host cell capable of expressing &agr; CX cleavage fragments of fibrinogen.