The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2002
Filed:
Feb. 20, 2001
Manuel Merlos Roca, Barcelona, ES;
Alberto Fernandez De Arriba, Barcelona, ES;
Fernando Cavalcanti De Maria, Barcelona, ES;
Agustí Miralles Acosta, Granollers, ES;
Mariano Sanchez Crespo, Valladolid, ES;
Julián Garcia Rafanell, Barcelona, ES;
Javier Forn Dalmau, Barcelona, ES;
J. Uriach & Cia, S.A., Barcelona, ES;
Abstract
The invention relates to the use of 2-hydroxy-4-trifluoromethylbenzoic acid derivatives as inhibitors of the activation of the nuclear transcription factor NF-&kgr;B. The invention also relates to the utilization of 2-hydroxy-4-trifluoromethylbenzoic acid derivatives for the preparation of medicaments to treat or prevent of pathologies associated to the activation of NF-&kgr;B and/or the expression of genes which are dependent on or regulated by, at least partially, NF&kgr;B in mammals, including humans.