The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2002
Filed:
Sep. 11, 2000
Applicant:
Inventor:
Raymond Paul Field, Bourne End, GB;
Assignee:
Lonza Group, AG, Zurich, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/509 ; C12N 5/00 ; C12P 2/104 ; A61K 3/514 ;
U.S. Cl.
CPC ...
C12N 1/509 ; C12N 5/00 ; C12P 2/104 ; A61K 3/514 ;
Abstract
Methods for obtaining a protein by culture of hybridoma cells, wherein said protein is an immunoglobulin, are disclosed. The methods involve culturing animal hybridoma cells in continuous presence of an alkanoic acid or salt thereof, which enhances protein production, wherein said alkanoic acid or salt thereof is present at 2 concentration range of 0.1 mM to 200 mM.