The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2002

Filed:

Jun. 30, 2000
Applicant:
Inventors:

David R. Olsen, Menlo Park, CA (US);

Jeff Prior, Redwood City, CA (US);

Louis C. Sehl, Redwood City, CA (US);

Donald G. Wallace, Menlo Park, CA (US);

Assignee:

Cohesion Technologies, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 2/106 ; C12N 9/48 ; C12N 9/74 ;
U.S. Cl.
CPC ...
C12P 2/106 ; C12N 9/48 ; C12N 9/74 ;
Abstract

New forms of ecarin, a procoagulant protein from venom, are described, as are polynucleotides encoding the new proteins, methods for production of the new proteins, and methods for activation of prothrombin using the new proteins. The new ecarins comprise a serine at position 396 of the protein. The new proteins may be used for activation of prothrombin, and are particularly useful for the production of recombinant thrombin.


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