The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2002
Filed:
Jun. 19, 2001
Applicant:
Inventors:
Eric M. Wakshull, Princeton, MA (US);
William M. Mackin, Charlton, MA (US);
Janet W. Zimmerman, Harvard, MA (US);
Leslie W. Fisette, Hubbardston, MA (US);
Assignee:
The Collaborative Group, Stony Brook, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 ; G01N 3/353 ; G01N 3/3566 ; C07H 1/00 ; C07H 5/04 ;
U.S. Cl.
CPC ...
C12Q 1/00 ; G01N 3/353 ; G01N 3/3566 ; C07H 1/00 ; C07H 5/04 ;
Abstract
Methods of isolating &bgr;(1-3)-glucan or &bgr;(1-3)-glucan-containing organisms in a sample, or of detecting the presence of &bgr;(1-3)-glucan or &bgr;(1-3)-glucan-containing organisms in a sample, utilizing binding agents for &bgr;(1-3)-glucan, such as LacCer, GalCer, globotriaosylceramide and asialoganglioside-GM1, are described. Methods of diagnosing fungal infection, by detecting &bgr;(1-3)-glucan or &bgr;(1-3)-glucan-containing organisms, are also described. Antibodies and kits useful in the methods are also disclosed.