The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2002
Filed:
Dec. 09, 1996
S. Christopher Bauer, New Haven, MO (US);
Mark Allen Abrams, St. Louis, MO (US);
Sarah Ruth Braford-Goldberg, St. Louis, MO (US);
Maire Helena Caparon, Chesterfield, MO (US);
Alan Michael Easton, Maryland Heights, MO (US);
Barbara Kure Klein, St. Louis, MO (US);
John P. McKearn, Glencoe, MO (US);
Peter O. Olins, Lafayette, CO (US);
Kumnan Paik, Wilmette, IL (US);
John Thomas, Town & Country, MO (US);
Other;
Abstract
The present invention relates to methods of ex-vivo expansion of hematopoietic cells by culturing hematopoietic cells in a growth medium comprising a variant of human interleukin-3 (hIL-3), which contains multiple amino acid substitutions and which may have portions of the native hIL-3 molecule deleted, and a hematopoietic growth factor. The present invention also relates to the ex-vivo expansion of hematopoietic cells for gene therapy. Additionally, the present invention relates to the use of the expanded hematopoietic cells for treating patients having a hematopoietic disorder.