The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2002

Filed:

Nov. 05, 1999
Applicant:
Inventors:

Alfonzo T. Perez, Lake Forest, IL (US);

Debra J. Asner, Morton Grove, IL (US);

Richard J. LaChapelle, Wilmette, IL (US);

John C. Alexander, Princeton, NJ (US);

Barbara Roniker, Chicago, IL (US);

Assignee:

G. D. Searle & Co., Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1585 ;
U.S. Cl.
CPC ...
A61K 3/1585 ;
Abstract

Combinations of an ACE inhibitor, an aldosterone antagonist, and a loop diuretic are described for use in treatment of circulatory disorders. Of particular interest are therapies using captopril, enalapril or lisinopril co-administered with spironolactone. This co-therapy would be particularly useful to reduce the death rate or the number of non-fatal hospitalizations or prevent the progression of congestive heart failure in patients with cardiovascular disease.


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