The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2002

Filed:

Jan. 29, 2001
Applicant:
Inventors:

Frederick Dana Cazer, Earlville, NY (US);

Gregory Eugene Parry, Lawrenceville, NJ (US);

Dennis Michael Billings, Norwich, NY (US);

Nancy Lee Redman-Furey, Smyrna, NY (US);

Assignee:

The Procter & Gamble Company, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1663 ; A61K 3/14406 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/1663 ; A61K 3/14406 ; C07D / ;
Abstract

The present invention discloses 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid sodium hemipentahydrate and monohydrate, methods of preparing the hemipentahydrate or monohydrate through control of the nucleation temperature and rate of crystallization and pharmaceutical compositions containing one or both of the hydrate forms.


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