The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2002
Filed:
Oct. 12, 2000
Applicant:
Inventors:
Lee Anne Beausang, Norfolk, MA (US);
Graham P. Lidgard, Wellesley, MA (US);
Thomas E. Miller, Franklin, MA (US);
Assignee:
Matritech, Inc., Newton, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/353 ; G01N 3/3567 ; G01N 3/3574 ; G01N 3/3531 ;
U.S. Cl.
CPC ...
G01N 3/353 ; G01N 3/3567 ; G01N 3/3574 ; G01N 3/3531 ;
Abstract
Disclosed is a method for detecting and quantitating soluble nuclear matrix proteins in body fluids and extracellular media. The method is useful for monitoring the viability of cells and tissue, for evaluating the progress of a disease or its treatment, and for evaluating the cytotoxicity of unknown compounds. Also disclosed are methods for inducing the release of nuclear matrix proteins in soluble form from cells.