The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2002
Filed:
Jun. 05, 2000
Applicant:
Inventors:
Raymond John Owens, Henley-on-Thames, GB;
Martyn Kim Robinson, Penn, GB;
Assignee:
Celltech Therapeutics Limited, Berkshire, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/628 ; C12N 1/513 ; A61K 9/127 ;
U.S. Cl.
CPC ...
C07K 1/628 ; C12N 1/513 ; A61K 9/127 ;
Abstract
This invention relates to whole antibodies of neutral isotype having specificity for E-selection, process for their preparation (using vectors), pharmaceutical compositions containing them, and their use in therapy (e.g. for inflammatory disorders) and diagnosis. Said antibodies are variants of natural antibodies altered in the F region, especially in the CH domain, so that the interactions with antibodies F receptors and complement are absent or very low.