The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2002

Filed:

Mar. 13, 2000
Applicant:
Inventors:

Sarkis Barret Kalindjian, Ban Stead, GB;

Ildiko Maria Buck, London, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/14164 ; A61K 3/14174 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/14164 ; A61K 3/14174 ; C07D / ;
Abstract

Compounds of formula (I) and their pharmaceutically acceptable salts are useful as histamine H receptor ligands. R and R are optional substituents such as C to C alkyl. R represents a bond or C to C (preferably C to C ) hydrocarbylene; R represents a bond or C to C (preferably C to C ) hydrocarbylene; R is hydrogen, C to C alkyl, R —O—(C to C )alkyl (wherein R is hydrogen or C to C alkyl), aryl, aryl(C to C )alkyl; R represents a bond or —NR —, wherein R is any of the groups mentioned above for R ; R is H or C to C hydrocarbyl (in which one or more hydrogen atoms may be replaced by halogen, and up to three carbon atoms may be replaced by oxygen, nitrogen or sulfur atoms); a is from 0 to 2; and b is from 0 to 3.


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