The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2002

Filed:

Jan. 18, 2000
Applicant:
Inventors:

Paul O. Sheppard, Granite Falls, WA (US);

Julia E. Novak, Bainbridge Island, WA (US);

Fenella Raymond, Seattle, WA (US);

Assignee:

ZymoGenetics, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C07H 2/102 ; C12N 1/500 ; C12N 1/509 ; C12N 1/563 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C07H 2/102 ; C12N 1/500 ; C12N 1/509 ; C12N 1/563 ;
Abstract

Studies indicate that mutations in tumor suppressor genes occur early in the process of carcinogenesis, and that these mutations are correlated with a subsequent development of cancer. The detection of such alterations would provide useful molecular markers for diagnosis, surveillance, early tumor identification and intervention, and prognosis. A novel human gene, designated as “Zsig62,” resides within a region of chromosome 16 that is associated with prostate and breast cancer, and that appears to contain tumor suppressor genes. Like a tumor suppressor gene, the Zsig62 gene is expressed in particular normal tissues, but not in tumors derived from those tissues.


Find Patent Forward Citations

Loading…