The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2002

Filed:

Jan. 05, 2000
Applicant:
Inventors:

Yves Dubaquie, San Francisco, CA (US);

Paul J. Fielder, Redwood City, CA (US);

Henry B. Lowman, El Granada, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/800 ; A61K 3/828 ; C07K 2/00 ; C07K 1/400 ;
U.S. Cl.
CPC ...
A61K 3/800 ; A61K 3/828 ; C07K 2/00 ; C07K 1/400 ;
Abstract

IGF-I variants having an alanine, glycine, or serine amino acid residue at position 16,25,49 or at positions 3 and 49 of native-sequence IGF-I are provided that are useful to treat a disorder characterized by dysregulation of the GH/IGF axis in a mammal, such as a renal disorder.


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