The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2002

Filed:

Mar. 03, 2000
Applicant:
Inventor:

Meng H. Heng, Belmont, CA (US);

Assignee:

Genencor International, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/00 ; C12N 9/02 ; C12N 9/04 ; C12N 9/10 ; C12N 9/26 ;
U.S. Cl.
CPC ...
C12N 9/00 ; C12N 9/02 ; C12N 9/04 ; C12N 9/10 ; C12N 9/26 ;
Abstract

The present invention provides a crystallization process wherein a starting temperature is selected such that a desirable crystal morphology (e.g., square) is obtained. A temperature shift is then introduced, providing that the shift is not enough to induce further nucleation, where the crystals continue to grow in the desirable fashion, but with different kinetics, e.g., a higher rate of crystallization. As a result, the process gives a crystalline product with desirable morphology at a higher crystallization rate. The starting temperature of the process can be between about 4° C. and 20° C. for no more than about 5 hours and the temperature shift of the process can be between about 22° C. and 60° C. for no more than about 20 hours.


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