The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2002
Filed:
May. 11, 2000
Paul Stead, Hertfordshire, GB;
Amy E. Wright, Ft. Pierce, FL (US);
Shirley A. Pomponi, Ft. Pierce, FL (US);
David Langley, Hertfordshire, GB;
Other;
Abstract
The subject invention concerns eryloside F, a novel disaccharide of the steroidal carboxylic acid penasterol. This compound can be isolated from an extract of the marine sponge . The compound is a potent thrombin receptor antagonist and, furthermore, inhibits human platelet aggregation. Longer chain penasterol oligosaccharides were also isolated and characterized but these had weaker activity than eryloside F. The subject invention also concerns methods for inhibiting thrombin receptor activity and methods for inhibiting platelet aggregation through the administration of eryloside F, or a salt, derivative or analog thereof.