The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2002

Filed:

Jul. 31, 1998
Applicant:
Inventors:

Maurice Joseph Anthony Clancy, Athlone, IE;

Kenneth Iain Cumming, Dublin, IE;

Michelle Caulfield, Ballhaunis, IE;

Assignee:

Elan Corporation, plc, Dublin, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/22 ; A61K 9/26 ; A61K 9/28 ; A61K 9/16 ;
U.S. Cl.
CPC ...
A61K 9/22 ; A61K 9/26 ; A61K 9/28 ; A61K 9/16 ;
Abstract

Controlled release oral pharmaceutical preparations are provided which comprise a therapeutically effective amount of tiagabine or a pharmaceutically acceptable salt thereof dispersed in a rate controlling polymeric matrix comprising at least one rate controlling polymer. The preparation can be formulated into oral dosage forms such as tablets or multiparticulates which provide therapeutically effective plasma levels of tiagabine for a period of at least 12 hours, preferably 24 hours or more. The preparation can provide tiagabine mean plasma concentrations equal to or greater than 50% of the maximum plasma concentration for at least 10 hours, preferably 14 hours, most preferably 16 hours or more.


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