The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2002
Filed:
May. 26, 2000
Applicant:
Inventors:
Jürgen Bongs, Wiesbaden, DE;
Johannes Meiwes, Idstein, DE;
Wolfgang Kruse, Hofheim, DE;
Klaus-Peter Koller, Bad Soden, DE;
Assignee:
Aventis Pharma Deutschland GmbH, Frankfurt am Main, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 3/500 ; C12N 9/96 ; C12N 9/14 ; C12N 9/80 ;
U.S. Cl.
CPC ...
C12P 3/500 ; C12N 9/96 ; C12N 9/14 ; C12N 9/80 ;
Abstract
A process is provided for delaying the deactivation of glutaryl amidase during catalysis. The amidase is, after maximum conversion of a substrate, separated off by filtration and can be reused in a subsequent reaction batch. In each reaction cycle, the amidase loses activity. The inactivation of the amidase can be delayed by bringing it into contact with a thiol during the reaction. The thiol is preferably 2-mercaptoethanol or cysteine.