The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2002
Filed:
Apr. 28, 2000
David E. Comings, Duarte, CA (US);
James P. MacMurray, Loma Linda, CA (US);
City of Hope, Duarte, CA (US);
Abstract
The present invention is directed to the C-45T polymorphism in the Sp1 binding region of the CCK gene and the role of genetic variants in the CCK gene as a risk factor for smoking and/or unsuccessful smoking cessation in women. In particular, the invention is directed to a method for diagnosing a polymorphism which is a risk factor for smoking comprising hybridizing a nucleic acid probe, which hybridizes specifically to an isolated DNA comprising a nucleotide sequence coding for human CCK containing a polymorphism described herein or its complement, to a patient's sample of DNA or RNA under stringent conditions which allows hybridization of said probe to nucleic acid comprising said polymorphism but prevents hybridization of said probe to a wild-type nucleic acid, wherein the presence of a hybridization signal indicates the presence of said polymorphism.