The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2002
Filed:
Jan. 11, 2000
Applicant:
Inventors:
Yukio Kato, Hiroshima, JP;
Takeshi Kawamoto, Yamaguchi, JP;
Assignee:
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/700 ; C07K 1/400 ;
U.S. Cl.
CPC ...
C07H 1/700 ; C07K 1/400 ;
Abstract
This invention provides a gene specifically expressed in differentiated human chrondrocytes. By culturing the chrondrocytes in the presence of dibutyryl cAMP, the chrondrocytes are cultured in a differentiated state and any gene is searched for which has a distinction in expression between differentiated chrondrocytes and dedifferentiated chrondrocytes. This allows the gene specifically expressed in the former to be obtained.