The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2002
Filed:
Apr. 01, 1999
Applicant:
Inventors:
Eliora Z. Ron, Tel Aviv, IL;
Judith Rishpon, Rehovot, IL;
Israel Biran, Beit Herot, IL;
Reuven Babai, Kadima, IL;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/353 ; C12Q 1/34 ; C12Q 1/42 ; C12N 9/16 ; C12N 9/26 ; C12N 5/00 ; C12N 1/34 ; C12N 1/20 ;
U.S. Cl.
CPC ...
G01N 3/353 ; C12Q 1/34 ; C12Q 1/42 ; C12N 9/16 ; C12N 9/26 ; C12N 5/00 ; C12N 1/34 ; C12N 1/20 ;
Abstract
A method and system for detecting a parameter of a host cell, a cell culture or medium is provided. A host cell is transfected with an expressible DNA sequence which is under expression control of an inducible promoter sequence. The promoter sequence is inducible in correlation with the parameter, the expressible sequence encoding an enzymatically active product which can catalyze a reaction giving rise to an electrical signal which is detectable in an electrochemical measurement. An electrical signal determined in an electrochemical system then serves as an indication for the parameter.