The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6388131 B1

PDF
Full Text
Expired
Date of Patent:
May. 14, 2002

Filed:

May. 31, 2001
Applicant:
Inventors:

Julio Cesar Medina, Belmont, CA (US);

David Louis Clark, Albany, CA (US);

John A. Flygare, Burlingame, CA (US);

Terry J. Rosen, Burlingame, CA (US);

Bei Shan, Foster City, CA (US);

Assignee:

Tularik, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/136 ; A61K 3/121 ; A61K 3/1275 ; A61K 3/118 ;
U.S. Cl.
CPC ...
A61K 3/136 ; A61K 3/121 ; A61K 3/1275 ; A61K 3/118 ;
Abstract

The invention provides compounds, compositions and methods relating to novel electrophilic aromatic derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly cancer, psoriasis, vascular restenosis, infections, atherosclerosis and hypercholesterolemia, or as lead compounds for the development of such agents. The compositions include compounds of the general Formula I:


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