The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2002
Filed:
May. 29, 1998
Applicant:
Inventors:
Rajeev S. Bhide, Langhorne, PA (US);
Charles Z. Ding, Plainsboro, NJ (US);
John T. Hunt, Princeton, NJ (US);
Soong-Hoon Kim, Lawrenceville, NJ (US);
Katerina Leftheris, Skillman, NJ (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/147 ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/147 ; C07D / ; C07D / ; C07D / ; C07D / ;
Abstract
Disclosed are quinoline and benzazepine derivatives that inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogenic protein Ras. Thus, the compounds are useful as anti-cancer agents. The compounds are also useful in the treatment of diseases other than cancer.