The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2002
Filed:
Oct. 21, 1998
Stefan Berg, Ekerö, SE;
Mats Linderberg, Södertälje, SE;
Svante Ross, Södertälje, SE;
Seth-Olov Thorberg, Strängnäs, SE;
Bengt Ulff, Södertälje, SE;
AstraZeneca AB, Sodertalje, SE;
Abstract
The present invention relates to new piperidinyl- or piperazinyl-substituted-3,4-dihydro-2H-1-benzopyran derivatives having formula (I) wherein X is N or CH; Y is NR CH , CH NR , NR CO, CONR or NR SO wherein R is H or C -C alkyl; R is H, C -C alkyl or C -C cycloalkyl; R is C -C alkyl, C -C cycloalkyl or (CH ) -aryl, wherein aryl is phenyl or a heteroaromatic ring containing one or two heteroatoms selected from N, O and S and which may be mono- or di-substituted; n is 0-4; R is C -C alkyl, C -C cycloalkyl, OCF , OCHF , OCH F, halogen, CONR R , CN, CF , OH, C -C alkoxy, NR R , SO CH , SO CF , SO NR R , an unsubstituted or substituted heterocyclic or heteroaromatic ring containing one or two heteroatoms selected from N and O, wherein the substituent(s) is(are) C -C alkyl; or COR ; wherein R , R and R are as defined above, as (R)-enantiomers, (S)-enantiomers or racemates in the form of a free base or pharmaceutically acceptable salts or solvates thereof, a process for their preparation, pharmaceutical compositions containing said therapeutically active compounds and to the use of said active compounds in therapy.