The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2002
Filed:
Feb. 23, 2001
Applicant:
Inventors:
Mark P. Chadwick, Cambridge, GB;
Stephen J. Russell, Rochester, MN (US);
Christian Buchholz, Frankfurt, DE;
Assignee:
BioFocus Discovery Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 ; C12Q 1/70 ; C12Q 1/68 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 7/00 ; C12Q 1/70 ; C12Q 1/68 ; C07H 2/104 ;
Abstract
Methods are disclosed whereby protease activity is directly linked to delivery of a transferable label to a target cell which expresses a protease, via fusion of viral display packages comprising the transferable label with the target cell. The methods can be used, inter alia, to identify proteases, including previously undiscovered proteases or variants of known proteases which may have altered substrate specificity.