The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2002
Filed:
Feb. 01, 2001
Applicant:
Inventors:
Lyle J. Arnold, Poway, CA (US);
Samuel P. Sawan, Tyngsborough, MA (US);
Paul H. Lee, Pleasanton, CA (US);
Assignee:
Incyte Genomics, Inc., Palo Alto, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C12N 1/511 ; C07K 1/600 ; C07K 2/00 ; C12M 1/36 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C12N 1/511 ; C07K 1/600 ; C07K 2/00 ; C12M 1/36 ;
Abstract
Methods are provide for modifying a solid support, such as a glass slide, by silylating with an agent having the formula H N—(CH ) —SiX where n is between 1 and 10, and X is independently chosen from OMe, OEt, Cl, Br, or I, then activating with a crosslinking reagent, followed by reacting with an amine-containing polymer. The support can optionally be reacted with a crosslinking reagent again. The support thus modified may be used to make arrays and microarrays where a plurality of targets are stably associated with the support and arranged in a defined manner.