The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2002
Filed:
Jun. 30, 1999
Applicant:
Inventors:
Richard B. Rothman, Bethesda, MD (US);
Kenner C. Rice, Bethesda, MD (US);
David Lewis, Rockville, MD (US);
Dorota Matecka, Washington, DC (US);
John R. Glowa, Shreveport, LA (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 1/300 ; C07D / ; C07D / ; A61K 3/1495 ; A61P 2/530 ;
U.S. Cl.
CPC ...
A61F 1/300 ; C07D / ; C07D / ; A61K 3/1495 ; A61P 2/530 ;
Abstract
The present invention provides sustained-release derivatives of hydroxylated analogs of substituted 1-[2[bis(aryl)methoxy]ethyl]-piperazines and -homopiperazines, pharmaceutical compositions comprising the same, and a method of using such sustained-release derivatives to bind the dopamine transporter to achieve a desired effect, such as antagonism of dopamine reuptake inhibitors, such as cocaine, or dopamine releasers or norepinephrine and/or serotonin reuptake inhibitors, such as methamphetamine.