The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6384282 B1

PDF
Full Text
Expired
Date of Patent:
May. 07, 2002

Filed:

Feb. 26, 2001
Applicant:
Inventors:

John F. Hartwig, Durham, CT (US);

Motoi Kawatsura, Chatham, NJ (US);

Oliver Loeber, New Haven, CT (US);

Assignee:

Yale University, New Haven, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; G01J 3/46 ; G01N 2/125 ;
U.S. Cl.
CPC ...
C07C / ; G01J 3/46 ; G01N 2/125 ;
Abstract

The present invention is directed to a process for addition of amines to carbon-carbon double bonds in a substrate, comprising: reacting an amine with a compound containing at least one carbon-carbon double bond in the presence a transition metal catalyst under reaction conditions effective to form a product having a covalent bond between the amine and a carbon atom of the former carbon-carbon double bond. The transition metal catalyst comprises a Group 8 metal and a ligand containing one or more 2-electron donor atoms. The present invention is also directed to enantioselective reactions of amine compounds with compounds containing carbon-carbon double bonds, and a calorimetric assay to evaluate potential catalysts in these reactions.


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Hartwig, John. (2002). Transition metal-catalyzed process for addition of amines to carbon-carbon double bonds (U.S. Patent No. 6384282). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6384282

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